Avi Domb
Professor
Habrew University of Jerusalem
Israel
Biography
Avi Domb is a professor and presently working as a president of Azrieli College of Engineering Jerusalem.Our interest is on the use of extended release of protein drugs as well as small bioactive molecules as a research tool for the determination of the effect of focal extended release on brain functions and as therapy for brain disorders. Local extended delivery of the neurotransmitters, glutamate and TRH in specific sites in the brain has been investigated. It was found that extended localized delivery provided different. In parallel to this investigation we have developed the Glade brain tumour implant for treating Glioma multiforme (in clinical use worldwide since its FDA approval in 1996). New anticancer formulations for direct injection into brain tissue have been developed and being tested for treating brain tumours.
Research Interest
Synthesis, characterization and applications of biopolymers. Medicinal and organic chemistry. Pharmaceutics and Pharmaceutical chemistry Controlled drug delivery. Nanoparticles and nanoformulations. Water purification systems, Bioactive polymers. Scaffolds for tissue engineering. Nucleic acid transfection agents. Forensic Sciences.